BioengineeringbioRxivPreprint
Allometric tissue-scale forces activate mechanoresponsive immune cells to drive pathological foreign body response to biomedical implants
J. Padmanabhan, K. Chen, D. Sivaraj…·G. C. Gurtner
The paper shows allometric tissue-scale forces drive pathological foreign body response by activating Rac2 signaling in immune cells, independent of implant properties.