Pharmacology & ToxicologybioRxivPreprint
Positive modulation of cerebellar α6GABAA receptors for treating essential tremor: a proof-of-concept study in harmaline-treated mice
Y.-H. Huang, M. T. Lee, W. Sieghart…·L.-C. Chiou
This study evaluates 6GABAAR-selective PAMs for treating essential tremor in harmaline-treated mice, finding they reduce tremor and restore burrowing activity.
DOI 10.1101/2021.04.19.440397