Cas9+ conditionally immortalized neutrophil progenitors as a tool for genome wide CRISPR screening for neutrophil differentiation and function
R. M. Jong, K. Ching, N. E. Garelis, A. Zilinskas, X. Nguyenla, S. Rawal, B. Hill, B. Luckie, L. Shallow, J. S. Cox, G. Barton, S. Stanley
This paper introduces a Cas9+ER-Hoxb8 neutrophil progenitor cell line for CRISPR screening to study neutrophil differentiation and function, identifying key genes like Cebpe and the WASH complex.
bioRxiv · Jul 19, 2022Immunology