L. Silva

Emerging chikungunya virus variants at the E1-E1 inter-glycoprotein spike interface impact virus attachment and Inflammation

This paper identifies emerging chikungunya virus E1 glycoprotein variants that enhance virus attachment, alter antibody neutralization, and increase inflammation in mice.

Structural basis of RICs iron donation for iron-sulfur cluster biogenesis

This paper identifies YtfE as an iron donor protein in E. coli's iron-sulfur cluster biogenesis, showing its interaction with IscU and IscS and the role of two glutamates in iron exit.

Diel dynamics of dissolved organic matter and heterotrophic prokaryotes reveal enhanced growth at the ocean's mesopelagic fish layer during daytime

The paper examines diel cycles in the mesopelagic zone, finding higher prokaryotic growth rates and DOM conversion efficiency during daytime due to fish activity.

CIS checkpoint deletion enhances the fitness of cord blood derived natural killer cells transduced with a chimeric antigen receptor

This paper combines CIS checkpoint deletion with CAR engineering in NK cells to enhance their metabolic fitness and anti-tumor activity in a lymphoma model.

CCR3 antagonist impairs estradiol induced eosinophil migration to the uterus in ovariectomized mice

The study shows that the CCR3 antagonist reduces estradiol-induced eosinophil migration and uterine edema in ovariectomized mice.