Author

M. Daher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

K. Chen· 4 shared D. Marin· 3 shared E. Gokdemir· 3 shared H. Shaim· 3 shared K. Rezvani· 3 shared L. Muniz-Feliciano· 3 shared M. Mendt· 3 shared N. Uprety· 3 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

K. Chen

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Author profile →

4 papers

Recent·Most cited

Transcriptional and phenotypic heterogeneity underpinning venetoclax resistance in AML

V. Mohanty, N. Baran, Y. Huang, C. L. Ramage, L. M. Cooper, S. He, R. Iqbal, M. Daher, CTD2 Research Network, J. W. Tyner, G. B. Mills, M. Konopleva, K. Chen

This study identifies four transcriptionally distinct venetoclax-resistant clusters in AML, revealing phenotypic, genetic, and drug response differences and their implications for treatment resistance.

bioRxiv · Jan 27, 2024 · PreprintCancer Biology

Generation of glucocorticoid resistant SARS-CoV-2 T-cells for adoptive cell therapy

R. Basar, N. Uprety, E. Ensley, M. Daher, K. Klein, F. Martinez, F. Aung, M. Shanley, B. Hu, E. Gokdemir, M. Mendt, F. Reyes Silva, S. Acharya, T. Laskowski, L. Muniz-Feliciano, , K. Rezvani

The paper expands SARS-CoV-2 T-cells from COVID-19 donors using IL-2/4/7 cytokines, achieving >1000-fold expansion with preserved function, and inactivates the glucocorticoid receptor to create glucocorticoid-resistant T-cells for adoptive therapy.

bioRxiv · Sep 15, 2020Immunology

Inhibition of the av integrin-TGF-b axis improves natural killer cell function against glioblastoma stem cells

H. Shaim, M. Hernandez Sanabria, R. Basar, F. Wang, M. Daher, D. Zamler, J. Gumin, K. Gabrusiewicz, Q. Miao, J. Dou, A. Alsuliman, L. Kerbauy, S. Acharya, V. Mohanty, P. Banerjee, , K. Rezvani

The paper shows that inhibiting the integrin-TGF-β axis enhances NK cell function against glioblastoma stem cells, suggesting it as a therapeutic target.

bioRxiv · Mar 30, 2020 · PreprintImmunology

CIS checkpoint deletion enhances the fitness of cord blood derived natural killer cells transduced with a chimeric antigen receptor

K. Rezvani, M. Daher, R. Basar, E. Gokdemir, N. Baran, N. Uprety, M. Mendt, L. Kerbauy, M. Hernandez Sanabria, N. Imahashi, A. Nunez, L. Li, M. Fathi, A. Rezvan, V. Mohanty, , Wei Inn

This paper combines CIS checkpoint deletion with CAR engineering in NK cells to enhance their metabolic fitness and anti-tumor activity in a lymphoma model.

bioRxiv · Mar 29, 2020 · PreprintImmunology