Cancer BiologybioRxiv
Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable Interaction with CTBP2
D. Pastoors, M. Havermans, R. Mulet-Lazaro…·R. Delwel
This study identifies EVI1's interaction with CTBP1/CTBP2 as critical for AML and shows that inhibiting this interaction can block leukemic growth.
DOI 10.1126/sciadv.adk9076