Author

L. Solie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

S. De Vleeschouwer· 2 shared A. Bikfalvi· 1 shared A. Claeys· 1 shared A. Eichmann· 1 shared A. Idbaih· 1 shared A. Martinez· 1 shared B. Cole· 1 shared B. Tavitian· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

S. De Vleeschouwer

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2 papers

Recent·Most cited

Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma

D. Panovska, P. Nazari, B. Cole, P.-J. Creemers, M. Derweduwe, L. Solie, S. Van Gassen, A. Claeys, T. Verbeke, Y. Saeys, D. Van Der Planken, F. M. Bosisio, E. Put, S. Bamps, P. Clement, , F. De Smet

The paper introduces PROSPERO, a single-cell assay to evaluate therapy response in glioblastoma by measuring molecular drug responses in fresh tumor samples, revealing limited therapeutic capacity and cellular plasticity.

bioRxiv · Oct 17, 2022 · PreprintCancer Biology

SLIT2-ROBO signaling in tumor-associated microglia/macrophages drives glioblastoma immunosuppression and vascular dysmorphia

L. H. Geraldo, Y. Xu, L. Jacob, L. Pibouin-Fragner, R. Rao, N. Maissa, M. Verreault, N. Lemaire, C. Knosp, C. Lesaffre, T. Daubon, J. Dejaegher, L. Solie, J. Rudewicz, T. Viel, , T. Mathivet

This study shows that SLIT2-ROBO signaling in tumor-associated microglia/macrophages promotes glioblastoma immunosuppression and vascular dysmorphia, and its inhibition reduces tumor growth and enhances therapy.

bioRxiv · Apr 12, 2021Cancer Biology