Author

A. Eichmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 6 Research Focus:cell signaling & trafficking· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:development & morphogenesis· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. Furtado· 3 shared L. Pibouin-Fragner· 3 shared M. Poulet· 3 shared B. Tavitian· 2 shared H. Park· 2 shared K. Boye· 2 shared L. H. Geraldo· 2 shared L. Jacob· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCell Biology

J. Furtado

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

EphrinA4/EphA4 controls blood pressure via arterial sympathetic innervation

E. SIMONNET, S. MARTIN, J. VILAR, E. ROY-VESSIERES, S. TAIB, V. MONCEAU, L. Pardanaud, N. BOUBY, A. Eichmann, J.-S. SILVESTRE, D. HENRION, I. V. BRUNET

This study shows EphrinA4 in arterial SMCs repels sympathetic axons, and its loss increases sympathetic innervation, leading to elevated blood pressure and hypertension under stress.

bioRxiv · Feb 3, 2023 · PreprintPhysiology

Netrin-1 binding to Unc5B regulates Blood-Retina Barrier integrity

J. Furtado, L. H. Geraldo, F. S. Leser, M. Poulet, H. Park, L. Pibouin-Fragner, A. Eichmann, K. Boye

This study shows Netrin-1 binding to Unc5B regulates blood-retina barrier integrity through Norrin/{beta}-catenin signaling.

bioRxiv · Jan 21, 2023 · PreprintCell Biology

Endothelial Unc5B controls blood-brain barrier integrity

K. Boye, L. H. M. Geraldo, J. furtado, L. Pibouin-fragner, M. Poulet, D. Kim, B. Nelson, Y. Xu, L. Jacob, N. Maissa, B. Tavitian, D. Agalliu, L. Claesson-Welsh, S. Ackerman, A. Eichmann

This study shows that endothelial Unc5B maintains blood-brain barrier integrity via Wnt/{beta}-catenin signaling, with potential therapeutic applications for CNS diseases.

bioRxiv · May 6, 2021Cell Biology

Defective flow-migration coupling causes arteriovenous malformations in hereditary hemorrhagic telangiectasia

H. Park, J. Furtado, M. Poulet, M. Chung, S. Yun, S. Lee, W. C. Sessa, C. A. Franco, M. A. Schwartz, A. Eichmann

This study shows that defective flow-migration coupling due to ALK1 loss causes arteriovenous malformations in HHT, with integrin-YAP/TAZ signaling as a potential therapeutic target.

bioRxiv · May 6, 2021Cell Biology

SLIT2-ROBO signaling in tumor-associated microglia/macrophages drives glioblastoma immunosuppression and vascular dysmorphia

L. H. Geraldo, Y. Xu, L. Jacob, L. Pibouin-Fragner, R. Rao, N. Maissa, M. Verreault, N. Lemaire, C. Knosp, C. Lesaffre, T. Daubon, J. Dejaegher, L. Solie, J. Rudewicz, T. Viel, , T. Mathivet

This study shows that SLIT2-ROBO signaling in tumor-associated microglia/macrophages promotes glioblastoma immunosuppression and vascular dysmorphia, and its inhibition reduces tumor growth and enhances therapy.

bioRxiv · Apr 12, 2021Cancer Biology

Activation of Smad 2/3 signaling by low shear stress mediates artery inward remodeling

E. Min, N. Baeyens, R. Hu, Z. Zhuang, M. Chen, B. Huang, G. Zarkada, A. Acheampong, K. McEntee, M. Simons, A. Eichmann, M. Schwartz

This study shows that low shear stress activates Smad 2/3 signaling in endothelial cells, leading to inward artery remodeling.

bioRxiv · Jul 5, 2019 · PreprintCell Biology