Author

L. T. Edgar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. A. Franco· 1 shared H. Gerhardt· 1 shared J. E. Moore· 1 shared J. Frattolin· 1 shared M. Jafarnejad· 1 shared M. O. Bernabeu· 1 shared S. C. Johnson· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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1 shared paperCell Biology

C. A. Franco

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2 papers

Recent·Most cited

ImmunologybioRxivJun 19, 2020

Lymph node swelling combined with temporary effector T cell retention aids T cell response in a model of adaptive immunity

S. C. Johnson, J. Frattolin, L. T. Edgar…·J. E. Moore

The paper models lymph node swelling's impact on T cell response, finding that temporary retention of effector T cells can counteract negative effects of swelling on immune response.

DOI 10.1098/rsif.2021.0464

biophysical modelinghost-pathogen & immune response

𝕏 PostBluesky

Cell BiologybioRxivFeb 7, 2020

On the preservation of vessel bifurcations during flow-mediated angiogenic remodelling

L. T. Edgar, C. A. Franco, H. Gerhardt, M. O. Bernabeu

This paper presents an agent-based model to study how endothelial cells integrate flow and collective cues to preserve vessel bifurcations during angiogenic remodelling, finding that both cues must be balanced for stability.

DOI 10.1371/journal.pcbi.1007715

deep learningcell type annotation

𝕏 PostBluesky