A Novel Mouse Model that Recapitulates the Heterogeneity of Human Triple Negative Breast Cancer
Z. O. Doha, X. Wang, N. Calistri, J. Eng, C. J. Daniel, L. Ternes, E. N. Kim, C. Pelz, M. Munks, C. Betts, N. Kirchberger, S. Kwon, E. Bucher, X. Li, T. Waugh, , R. C. Sears
This paper develops a novel mouse model of TNBC by combining MYC amplification and PTEN deletion, showing it recapitulates human TNBC heterogeneity through omic analyses.
bioRxiv · Oct 7, 2022 · PreprintCancer Biology