Genetic Modification to Design a Stable Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain as a COVID-19 Vaccine Candidate
W.-H. Chen, J. Wei, R. T. Kundu, R. Adhikari, Z. Liu, J. Lee, L. Versteeg, C. Poveda, B. Keegan, M. J. Villar, A. C. de Araujo Leao, J. Altieri Rivera, P. M. Gillespie, J. Pollet, U. Strych, , M. E. Bottazzi
The paper genetically modifies SARS-CoV-2 RBD variants in yeast to identify a more stable and manufacturable vaccine candidate.
bioRxiv · Nov 9, 2020Immunology