BDNF receptor balance gates AgRP-to-PVH fiber density and stimulation evoked feeding across caloric states
O. Yipkin Calhan, Sara K Michel-Le, Elizabeth Godschall, Shishir S Sriramoju, Margaret Nunnaly, Sophia Ogilvie, Kaleigh I. West, Orien Dong-Ang Li, L. Vo, Taha Buğra Güngül, Prathik Nalamalapu, Marcos Torales Montes, Lloyd Choi, John N. Campbell, Ali D. Güler, Christopher D. Deppmann
The paper shows that the balance of BDNF receptors TrkB and p75NTR in AgRP neurons controls PVH fiber density and stimulation-evoked feeding across different caloric states.
bioRxiv · Sep 12, 2025 · PreprintNeuroscience