Author

D. Le

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Animal Behavior & Cognition· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:behavioral assay· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Bui· 1 shared A. D. Tward· 1 shared A. Flores· 1 shared A. Gomez· 1 shared A. Ho· 1 shared A. I. Derman· 1 shared A. Maynard· 1 shared A. Prichard· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperMicrobiology

A. Bui

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Hematopoietic stem and progenitor cells improve survival from sepsis by boosting immunomodulatory cells

D. E. Morales-Mantilla, B. Kain, D. Le, A. Flores, S. Paust, K. King

This study shows that infusing hematopoietic stem and progenitor cells (HSPCs) into septic mice improves survival by increasing immunomodulatory cells, despite similar pathogen loads.

bioRxiv · Oct 26, 2021Immunology

Human melanocyte development and melanoma dedifferentiation at single cell resolution

R. L. Belote, D. Le, A. Maynard, U. E. Lang, A. Sinclair, V. Planells-Palop, L. S. Baskin, A. D. Tward, S. Darmanis, R. L. Judson-Torres

This study characterizes human melanocyte development and dedifferentiation using single-cell RNA-sequencing, identifying site-specific subpopulations and transcriptional programs distinct from model systems.

Nature Cell Biology · Sep 2, 2021Peer-reviewedCancer Biology

Isolation and characterization of Streptomyces bacteriophages and Streptomyces strains encoding biosynthetic arsenals

E. T. Montano, J. F. Nideffer, L. Brumage, M. Erb, A. I. Derman, J. P. Davis, E. Estrada, S. Fu, D. Le, A. Vuppala, C. Tran, E. Luterstein, S. Lakkaraju, S. Panchagnula, C. Ren, , J. Pogliano

This study identifies novel Streptomyces strains and phages with potential for antibiotic discovery and genetic manipulation.

bioRxiv · Jun 22, 2020 · PreprintMicrobiology

A human ex vivo dengue virus neutralization assay identifies priority antibodies and epitopes for vaccines and therapeutics.

T. Vu, H. Clapham, V. Huynh, L. Vo, D. Le, N. Vu, G. Nguyen, T. Huynh, K. Duong, V. Tran, H. Huynh, T. Huynh, T. Nguyen, N. Nguyen, T. Luong, , C. Simmons

This study develops an ex vivo dengue virus neutralization assay using mosquitoes to identify potent human monoclonal antibodies and their epitopes for vaccine and therapeutic development.

bioRxiv · Jan 10, 2019Immunology

Mechanism and resistance for antimycobacterial activity of a fluoroquinophenoxazine compound

P. K. Garcia, T. Annamalai, W. Wang, R. S. Bell, D. Le, P. Martin Pancorbo, S. Sikandar, A. Seddek, X. Yu, D. Sun, A.-C. Uhlemann, P. B. Tiwari, F. Leng, Y.-C. Tse-Dinh

This study investigates the antimycobacterial mechanism of FP-11g, a fluoroquinophenoxazine compound, and identifies resistance mechanisms in Mycobacterium smegmatis.

bioRxiv · Nov 7, 2018Microbiology

Behavioral Analysis of Substrate Texture Preference in a Leech, Helobdella austinensis

R. C. Kim, D. Le, K. Ma, E. A. C. Heath-Heckman, N. Whitehorn, W. B. Kristan, D. A. Weisblat

The paper investigates substrate texture preference in leeches by testing two behavioral mechanisms under controlled conditions.

bioRxiv · Sep 5, 2018Animal Behavior & Cognition