ImmunologybioRxiv
Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 responses
S. Ndeupen, A. Bouteau, C. Herbst…·B. Igyarto
This study shows that Langerhans cells and cDC1s have redundant roles in mRNA-LNP-induced anti-influenza and anti-SARS-CoV-2 immunity, with IL-6 driving Tfh and humoral responses independently of neutrophils.
DOI 10.1371/journal.ppat.1010255