BiophysicsbioRxiv
Deterministic Early Endosomal Maturations Emerge From a Stochastic Trigger-and-Convert Mechanism
H. M. York, K. Joshi, C. S. Wright…·S. Arumugam
The paper tracks endosomal maturation events using advanced imaging and simulations, revealing that maturation is driven by heterotypic EEA1-mediated interactions rather than autonomous stochastic processes.
DOI 10.1038/s41467-023-40428-1