Author

Lan Zhang

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

Hengxiang Yu· 2 shared Jun ZhangiD· 2 shared Rong-Chun Tang· 2 shared Shijin Geng· 2 shared Yunxuan Zhou· 2 shared A R ZhangiD· 1 shared Ao ZhangiD· 1 shared Christopher Warren· 1 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

Hengxiang Yu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structure-based design of soluble prefusion-stabilized herpes simplex virus type 2 glycoprotein B antigens

Madeline R. Sponholtz, Daphne Ma, Emmanuel Ndashimye, Patrick O. Byrne, Yi Shu, Christopher Warren, Nithya Thambi, Ryan S. McCool, Matthew D. Slein, Nicole V. Johnson, William A. Rose, Lan Zhang, Eberhard Dürr, Dai Wang, Jason S. McLellan

This study designs prefusion-stabilized HSV-2 gB antigens using structure-based methods and evaluates their immunogenicity, finding no improvement in neutralizing antibody titers compared to postfusion constructs.

Cell Reports · Sep 1, 2026Peer-reviewedMicrobiology

IGF2BP3 amplifies antiviral innate immunity with implications for autoimmune diseases

Ao Zhang, Shijin Geng, Rong-Chun Tang, Hengxiang Yu, Yunxuan Zhou, Lan Zhang, Xiuyuan Sun, Jun Zhang

This paper identifies IGF2BP3 as a critical amplifier of antiviral innate immunity, showing it enhances viral RNA sensing and IFN-I production, and reveals its role in autoimmune diseases.

bioRxiv · Aug 6, 2026 · PreprintImmunology

An in situ generated CAR-M with IFNg and negative dominance Sirpa isoform augments hepatocellular carcinoma immunotherapy

Xiang Li, Jing Hu, Tian Zhang, Hongceng Li, Quanrong Lai, Tao Wang, Yuxin Liu, Lan Zhang, Yonglong Wei, Wei Shi, Panpan Zhang

This paper develops a novel CAR-M targeting GPC3 with IFN-gamma and SIRPECD to enhance anti-tumor activity in hepatocellular carcinoma.

Journal of Nanobiotechnology · May 26, 2026Peer-reviewedCancer Biology

The gut microbiota metabolite Urolithin A mitigates JAK signaling to suppress cytokine-mediated autoimmune diseases

Shijin Geng, Rong-Chun Tang, Hengxiang Yu, A R Zhang, Shuang‐Shuang Yu, Yunxuan Zhou, Lan Zhang, Jun Zhang

This study identifies Urolithin A as a gut microbiota metabolite that inhibits JAK signaling to reduce cytokine-driven autoimmune disease pathology.

bioRxiv · May 12, 2026 · PreprintImmunology