Developmental BiologybioRxivPreprint
Y705 and S727 are required for mitochondrial import and transcriptional activities of STAT3 and regulate proliferation of embryonic and tissue stem cells
Margherita Peron, Giacomo Meneghetti, Alberto Dinarello…·Francesco Argenton
This paper identifies Y705 and S727 phosphorylation sites on STAT3 as critical for its mitochondrial import and transcriptional activity, which regulate stem cell proliferation in zebrafish and mouse models.