BiochemistryNucleic Acids ResearchPeer-reviewed
Motif-VI Loop Acts as a Nucleotide Valve in the West Nile Virus NS3 Helicase
Priti Roy, Zachary Walter, Lauren Berish…·Martin McCullagh
This study identifies the motif-VI loop as a nucleotide valve in the West Nile Virus NS3 helicase, showing its role in ATP hydrolysis and viral replication through molecular simulations and experimental validation.
8 citations