Priti Roy

This paper investigates how the L405D mutation in SARS-CoV-2 nsp13 decouples ATP hydrolysis from RNA translocation by altering conformational dynamics.

This study reveals ATP-dependent coupling between nucleotide and RNA affinity in WNV NS3h, showing how motif VIL residues modulate RNA binding through conformational changes.

This study identifies the motif-VI loop as a nucleotide valve in the West Nile Virus NS3 helicase, showing its role in ATP hydrolysis and viral replication through molecular simulations and experimental validation.