Author

Lei Han

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genetics· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:database / resource· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

Ang HuiD· 1 shared Biyun ZhuiD· 1 shared Cheng Ye· 1 shared Chong Cui· 1 shared Dan MuiD· 1 shared Daqi Wang· 1 shared Guangbin Sun· 1 shared Guannan Geng· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperEcology

Ang HuORCID

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3 papers

Recent·Most cited

Toward a global chemogeography of dissolved organic matter: a molecular trait dataset across Earth systems

lei han, Kang Song, James Stegen, Ang Hu

The paper compiles and harmonizes a global dataset of dissolved organic matter molecular traits from 3,999 samples across diverse environments to enable cross-system comparisons and global chemogeography analysis.

bioRxiv · Sep 23, 2026 · PreprintEcology

Combination of engineered cell type-specific promoters and a high-efficiency AAV capsid restores hearing in adult DFNB1 mice model with demonstrated safety in nonhuman primate

Shao Wei Hu, Cheng Ye, Guannan Geng, Yicheng Zeng, Yihan Bao, Sen Zhang, Chong Cui, Yingting Zhang, Dan Mu, Daqi Wang, Xintai Fan, Ziting Chen, Biyun Zhu, Shuang Han, Hongxing Wang, , Yilai Shu

This paper demonstrates hearing restoration in adult DFNB1 mice using engineered promoters and an AAV capsid, with safety confirmed in nonhuman primates.

bioRxiv · Apr 18, 2026 · PreprintGenetics

Site-specific integration of transposon via engineered piggyBac transposase

Naiqing Xu, Lei Han, Xiaohan Hu, Yuan Fang, Limeng Wu, Xi Wang, Haoyang Tu, Xiaogang Deng, Weili Cong, Kailiang Sun, Yi Jin, Xiaoyang Wu

This paper demonstrates a method using engineered piggyBac transposase and CRISPR/Cas9 to achieve targeted integration of large DNA fragments into the human genome with high specificity and efficiency.

bioRxiv · Jan 21, 2026 · PreprintGenetics