Author

Li Gu

Sichuan UniversityPrimary ORCID profile (0000-0001-9508-5673 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Li GuiD1 paper · University of California San Diego

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Aïda MeghraouiiD· 1 shared Andrew H. Chiang· 1 shared Anneroos E NederstigtiD· 1 shared Arnaud GuilléiD· 1 shared Chantal DesdouetsiD· 1 shared Christophe LachaudiD· 1 shared Clémence Ginet· 1 shared Craig VierraiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Aïda MeghraouiORCID

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2 papers

Recent·Most cited

TERT drives liver tumorigenesis beyond telomere elongation

Laura Braud, Julien Vernerey, Arnaud Guillé, Pierre Cordier, Clémence Ginet, Tom Egger, Manuel Bernabe, Dmitri Churikov, Quentin Da Costa, Aïda Meghraoui, Chantal Desdouets, Li Gu, François Bertucci, Christophe Lachaud, Vincent Géli

This study shows TERT promotes liver tumors independently of telomere elongation, revealing molecular and metabolic features relevant to immunotherapy response.

Life Science Alliance · Jun 12, 2026Peer-reviewedCancer Biology

Design of linked-domain protein inhibitors of UBE2D as tools to study cellular ubiquitination

Zara Bukhari, Li Gu, Anneroos E Nederstigt, Logan J. Cope, Derek L. Bolhuis, Kim Harvey, Tristan Allen, Spencer Hill, Yujie Yang, Guy Lawson, Lu Cai, Tommy Tran, Leah Pineda, Leanne M. Low, Andrew H. Chiang, , Joseph S. Harrison

This paper designs a protein inhibitor for UBE2D enzymes to study their role in ubiquitination, showing it reduces Ub degradation and proteotoxic stress in HeLa cells.

Cell chemical biology · Dec 1, 2025Peer-reviewedBiochemistry