Author

Manuel Bernabe

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Christophe LachaudiD· 3 shared Julien VernereyiD· 3 shared Laura BraudiD· 3 shared Vincent GéliiD· 3 shared Dmitri ChurikoviD· 2 shared Jesús GiliD· 2 shared Will Scott· 2 shared Aïda MeghraouiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersPhysiology

Christophe LachaudORCID

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Author profile →

3 papers

Recent·Most cited

TERT drives liver tumorigenesis beyond telomere elongation

Laura Braud, Julien Vernerey, Arnaud Guillé, Pierre Cordier, Clémence Ginet, Tom Egger, Manuel Bernabe, Dmitri Churikov, Quentin Da Costa, Aïda Meghraoui, Chantal Desdouets, Li Gu, François Bertucci, Christophe Lachaud, Vincent Géli

This study shows TERT promotes liver tumors independently of telomere elongation, revealing molecular and metabolic features relevant to immunotherapy response.

Life Science Alliance · Jun 12, 2026Peer-reviewedCancer Biology

Non-canonical TERT function mitigates adipose tissue inflammation in obesity by modulating stem cell-macrophage communication and macrophage states

Laura Braud, Andrea Ninni, Antonio M.A. Miranda, Émilie Baudelet, Julien Vernerey, Marina Villaverde, Francesca Sciarretta, Manuel Bernabe, Léa Girondier, Ilaria Elia, Jesús Gil, Stéphane Audebert, Jean‐Marc Brondello, Christophe Lachaud, Will Scott, , Vincent Géli

This study shows that TERT expression in adipose tissue reduces inflammation and improves metabolism in obesity by altering macrophage states and stem cell-macrophage communication.

bioRxiv · Dec 18, 2025 · PreprintPhysiology

TERT prevents obesity-induced metabolic disorders by promoting adipose stem cell expansion and differentiation

Laura Braud, Manuel Bernabe, Julien Vernerey, Antonio M. A. Miranda, Andrea Dominguez, Dmitri Churikov, Manon Richaud, Liam McAllan, Christophe Lachaud, Jesús Gil, Will Scott, Vincent Géli

This study shows that TERT reduces obesity-induced metabolic disorders by promoting adipose stem cell expansion and differentiation, and remodeling macrophages in adipose tissue.

bioRxiv · Jan 6, 2025 · PreprintPhysiology