Cancer BiologybioRxivPreprint
Deletion of genes encoding PU.1 and Spi-B leads to B cell acute lymphoblastic leukemia associated with driver mutations in Janus Kinases
Carolina R. Batista, Michelle Lim, Anne-Sophie Laramée…·Rodney P. DeKoter
This study shows that deletion of PU.1 and Spi-B in mice leads to B-ALL with JAK mutations as secondary drivers.
DOI 10.1101/291054