BiochemistrybioRxivPreprint
The crystal and cryo-EM structures of PLCγ2 reveal dynamic inter-domain recognitions in autoinhibition
Young-Cheul Shin, Ashlee Marie Plummer-Medeiros, Alison Mungenast…·Yu Chen
The paper determines crystal and cryo-EM structures of PLCγ2 in autoinhibited states and bound to FGFR1 kinase domain, revealing dynamic inter-domain interactions in autoinhibition.
DOI 10.1101/2023.09.07.556539