Ling Wang

NO modulates human airway smooth muscle function by altering glucose-6-phosphate dehydrogenase effects on sGC function in asthma

This study shows that NO modulates airway smooth muscle function in asthma by altering G6PD effects on sGC function through redox regulation and heme-maturation.

Superior intracellular detection of cytokines, transcription factors, and phosphoproteins by CyTOF compared with fluorescent cytometry

This study compares CyTOF with fluorescent cytometry for detecting intracellular markers, finding CyTOF provides superior resolution for phosphoproteins, transcription factors, and cytokines, enabling better immune cell clustering and discovery of unique populations.

Peptide YY: a novel Paneth cell antimicrobial peptide that maintains fungal commensalism

This paper identifies peptide YY (PYY) as a novel antimicrobial peptide produced by Paneth cells with selective antifungal activity against Candida albicans hyphae, maintaining gut fungal commensalism.

Targeted Deletion of Vitamin D receptor Gene in Mammalian Cells by CRISPR/Cas9 Systems

This study demonstrates that CRISPR/Cas9 can delete large genomic segments in human and mouse cells by using two sgRNAs targeting conserved regions of the VDR gene.