Amal Kambal

This study shows that Streptococcus pneumoniae precolonization reduces RSV levels and modulates epithelial transcriptional responses to RSV infection more than other nasal bacteria.

This study uses human nasal epithelial organoids to investigate how different bacteria colonize nasal tissue and induce cytokine responses, finding differential effects on chemokines and inflammasome signaling.

This study develops human bladder organoids to model UTIs and phage therapy, showing phage reduces bacterial loads and inflammation during infection.

This study compares RSV infection responses in pediatric and adult nose organoids, finding pediatric organoids show greater susceptibility, cytokine response, and cellular damage.

This paper identifies peptide YY (PYY) as a novel antimicrobial peptide produced by Paneth cells with selective antifungal activity against Candida albicans hyphae, maintaining gut fungal commensalism.