Author

Lisa Mohamet

GlaxoSmithKline (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1

Frequent Co-Authors

Benedetta Carbone· 2 shared Aikaterini GeladakiiD· 1 shared Alastair D. ReithiD· 1 shared Alessandro Di Tullio· 1 shared Alice RockliffeiD· 1 shared Andres Quintero Moreno· 1 shared Bin Sun· 1 shared Charlie Haslam· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

Benedetta Carbone

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 14, 2026

High-throughput platforms for genetic perturbation screening using CRISPR/Cas9 in human iPSC-derived macrophages for drug discovery

Matteo Martufi, Eleni Karagianni, Tasos Papanikos…·Lisa Mohamet

The paper establishes a CRISPR/Cas9 screening platform in hiPSC-derived macrophages to identify genetic targets influencing inflammatory responses and functional phenotypes.

DOI 10.64898/2026.09.11.750978

humanbulk RNA-seq

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NeurosciencebioRxivPreprintJun 10, 2025

A CRISPR-CAS9 high throughput machine-learning platform for modulation of genes involved in Parkinson's disease-associated PINK1-mitophagy in iPSC-derived dopaminergic neurons

Marc P. M. Soutar, Benedetta Carbone, Petya Kindalova…·Hélène Plun‐Favreau

The paper develops a CRISPR-CAS9 platform with machine learning to study PINK1-mitophagy in Parkinson's disease using iPSC-derived neurons, identifying key genes and validating their roles.

DOI 10.1101/2025.06.10.658840

humanCRISPR screen

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BioinformaticsACS Pharmacology & Translational SciencePeer-reviewedDec 12, 2022

A Scalable 3D High-Content Imaging Protocol for Measuring a Drug Induced DNA Damage Response Using Immunofluorescent Sub-nuclear γH2AX Spots in Patient Derived Ovarian Cancer Organoids

Hakan Keles, Christopher Schofield, Helena Rannikmäe…·Lisa Mohamet

This paper develops a scalable 3D imaging protocol to measure DNA damage response in ovarian cancer organoids using γH2AX staining and shows its effectiveness with Etoposide treatment.

13 citations

humanimaging

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