Pharmacology & ToxicologybioRxivPreprint
Go/z-biased coupling profile of the dopamine D3 receptor
Lucrezia Zanetti, Luca Franchini, Shirsha Saha…·Cesare Orlandi
The paper investigates the G protein coupling profile of dopamine D3 receptor, finding it selectively activates Go and Gz subtypes but not Gi proteins, with structural determinants identified.
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