BiochemistryNature Structural & Molecular BiologyPeer-reviewed
An Atypical E3 Ligase Module in UBR4 Mediates Destabilization of N-degron Substrates
Lucy Barnsby-Greer, Peter D. Mabbitt, Marc-André C. Déry…·Satpal Virdee
This study identifies and characterizes a novel E3 ligase module in UBR4, revealing its structural and biochemical specificity for UBE2A and its role in the N-degron pathway.
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