Author

Lucy Scott

Institute of Genetics and Cancer

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Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein design· 1

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Alex von KriegsheimiD· 1 shared Andrew J. WoodiD· 1 shared Bin GuiD· 1 shared Ersi ChristodoulouiD· 1 shared Gillian C.A. TayloriD· 1 shared Janet RossantiD· 1 shared Jennifer Margaret BrisbaneiD· 1 shared Lewis MacdonaldiD· 1 shared

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2022-2022 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperGenetics

Alex von KriegsheimORCID

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1 paper

Recent·Most cited

GeneticseLifePeer-reviewedJun 23, 2022

Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons

Lewis Macdonald, Gillian C.A. Taylor, Jennifer Margaret Brisbane…·Andrew J. Wood

This paper develops CRISPR-engineered mouse lines for rapid and specific degradation of endogenous proteins in vivo, revealing stage-specific requirements for condensin complexes in lymphocyte division.

48 citationstop 5%

mouseexperimental assay

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