PhysiologybioRxivPreprint
Chronopharmacological targeting of mitochondrial dihydroorotate dehydrogenase prevents diet-induced obesity in male mice
Florian Atger, M Durand, Mikaël Croyal…·David Jacobi
This study shows that timing DHODH inhibition during dawn reduces obesity in male mice by improving mitochondrial function and metabolic rhythms.
DOI 10.64898/2026.04.18.719366