Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
E. Kon, Y. Levy, U. Elia, H. Cohen, I. Halevy, M. Aftalion, A. Ezra, E. Bar-Haim, G. S. Naidu, Y. Diesendruck, S. Rotem, N. Ad-El, M. Goldsmith, E. Mamroud, D. Peer, O. Cohen
This study develops an mRNA-LNP vaccine against Yersinia pestis, showing it provides full protection against infection in animals.
bioRxiv · Aug 7, 2022 · PreprintMicrobiology
Y. Vagima, D. Gur, M. Aftalion, S. Moses, Y. Levy, A. Makovitzki, T. Holtzman, Z. Oren, Y. Segula, E. Fatelevich, A. Tidhar, A. Zauberman, S. Rotem, E. Mamroud, I. Steinberger-Levy
This paper shows that combining phage therapy with ceftriaxone improves survival in a mouse model of pneumonic plague caused by multidrug-resistant Yersinia pestis.
bioRxiv · Feb 7, 2022Microbiology
S. Melamed, B. Politi, E. Grauer, H. Achdout, M. Aftalion, D. Gur, H. Tamir, Y. Yahalom-Ronen, S. Maimon, E. Yitzhak, S. Weiss, A. Rosner, N. Erez, S. Yitzhaki, S. C. Shapira, , T. Israely
This study uses group activity monitoring in hamsters and mice to assess SARS-CoV-2 infection, convalescence, and vaccine efficacy.
Frontiers in Bioengineering and Biotechnology · Oct 1, 2021Peer-reviewedImmunology
M. Israeli, Y. Finkel, Y. Yahalom-Rone, N. Paran, T. Chitlaru, O. Israeli, I. Cohen-Gihon, M. Aftalion, R. Falach, U. Elia, I. Nemet, L. Kliker, M. Mandelboim, A. Beth-Din, T. Israely, , A. Bercovich-Kinori
This study uses CRISPR screens to identify host factors critical for SARS-CoV-2 infection, finding GATA6 as a key modulator of ACE2 expression and viral entry.
bioRxiv · Jul 19, 2021 · PreprintMicrobiology
T. Noy-Porat, A. Edri, R. Alcalay, E. Makdasi, D. Gur, M. Aftalion, Y. Evgy, A. Beth-Din, Y. Levy, E. Epstein, O. Radinsky, A. Zauberman, S. Lazar, S. Yitzhaki, H. Marcus, , O. Mazor
This study shows that Fc-independent monoclonal antibodies can neutralize SARS-CoV-2 in mice, reducing viral load and preventing mortality without Fc-dependent effector functions.
bioRxiv · May 15, 2021Immunology
E. Makdasi, A. Zvi, R. Alcalay, T. Noy-Porat, E. Peretz, A. Mechaly, Y. Levy, E. Epstein, T. Chitlaru, A. Tennenhouse, M. Aftalion, D. Gur, N. Paran, H. Tamir, O. Zimhony, , R. Rosenfeld
This study evaluates the neutralization potency of four SARS-CoV-2 mAbs against spike mutations and two variants of concern, finding that MD65 and BL6 retain effectiveness against B.1.1.7 and B.1.351.
bioRxiv · Apr 1, 2021Immunology
U. Elia, S. Rotem, E. Bar-Haim, S. Ramishetti, G. S. Naidu, D. Gur, M. Aftalion, M. Israeli, A. Bercovich-Kinori, R. Alcalay, E. Makdasi, T. Chitlaru, R. Rosenfeld, T. Israely, S. Melamed, , O. Cohen
This study evaluates an mRNA vaccine against SARS-CoV-2 in hACE2 transgenic mice, showing 70% protection against a lethal infection.
bioRxiv · Mar 29, 2021Microbiology
T. Noy-Porat, A. Mechaly, Y. Levy, E. Makdasi, R. Alcalay, D. Gur, M. Aftalion, R. Falach, S. Leviatan Ben-Arye, S. Lazar, A. Zauberman, E. Epstein, T. Chitlaru, S. Weiss, H. Achdout, , R. Rosenfeld
This study identifies and characterizes neutralizing antibodies targeting the SARS-CoV-2 spike N-terminal domain, showing their protective efficacy in mice.
bioRxiv · Feb 2, 2021Immunology
R. Falach, L. Bar-On, S. Lazar, T. Kadar, O. Mazor, M. Aftalion, D. Gur, O. Shifman, O. Israeli, I. Cohen-Gihon, G. Zaide, H. Gutman, Y. Evgy, Y. Vagima, E. Makdasi, , T. Sabo
This study shows that CD-1 mice with induced pulmonary comorbidities develop severe lung inflammation and high mortality after SARS-CoV-2 infection.
bioRxiv · Oct 28, 2020 · PreprintPathology
R. Rosenfeld, T. Noy-Porat, A. Mechaly, E. Makdasi, Y. Levy, R. Alcalay, R. Falach, M. Aftalion, E. Epstein, D. Gur, T. Chitlaru, E. B. Vitner, S. Melamed, B. Politi, A. Zauberman, , O. Mazor
This study shows that the human monoclonal antibody MD65 can rescue 100% of SARS-CoV-2 infected mice when administered up to 3 days post-exposure.
bioRxiv · Oct 26, 2020Immunology