Author

M. Aleckovic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:clinical cohort / trial· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

S. Srinivasan· 2 shared T.-H. Nguyen· 2 shared A. Mahmoodi· 1 shared G. Coricor· 1 shared J. Lee· 1 shared J. M. M. Oneto· 1 shared J. M. McFarland· 1 shared J. M. Mejia Oneto· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

S. Srinivasan

Mutual co-authors in cluster

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2 papers

Recent·Most cited

SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

S. Srinivasan, N. A. Yee, M. Zakharian, M. Aleckovic, A. Mahmoodi, T.-H. Nguyen, J. M. Mejia Oneto

This paper demonstrates SQ3370, a click chemistry-activated cancer therapeutic, is safe in humans and shows translatability across species with effective tumor activation and immune response.

bioRxiv · Mar 28, 2023 · PreprintPharmacology & Toxicology

Click chemistry selectively activates an auristatin protodrug with either intratumoral or systemic tumor-targeting agents

J. M. McFarland, M. Aleckovic, G. Coricor, S. Srinivasan, M. Tso, J. Lee, T.-H. Nguyen, J. M. M. Oneto

This paper demonstrates the activation of a protodrug, SQP22, using click chemistry with tumor-targeting agents, showing anti-tumor effects in murine models with reduced toxicity.

bioRxiv · Mar 28, 2023Pharmacology & Toxicology