Cancer BiologybioRxivPreprint
Androgen-mediated TGFβ expression suppresses anti-tumor neutrophil response in bone metastatic prostate cancer
M. Alsamraae, D. Costanzo-Garvey, B. A. Teply…·L. M. Cook
This study identifies androgen-mediated TGFβ expression as a mechanism suppressing anti-tumor neutrophil response in bone metastatic prostate cancer and shows that combining ADT with TGFβ receptor inhibition restores neutrophil cytotoxicity.
DOI 10.1101/2022.12.30.522329