BiochemistrybioRxivPreprint
The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding.
C. J. Mycroft-West, D. Su, S. Elli…·M. A. Skidmore
The paper shows that SARS-CoV-2 Spike S1 RBD undergoes a conformational change when bound to heparin, suggesting potential for heparin as a therapeutic.
DOI 10.1101/2020.02.29.971093