Cancer BiologyNature CommunicationsPeer-reviewed
Clonal Evolution of Acute Myeloid Leukemia Revealed by High-Throughput Single-Cell Genomics
K. Morita, F. Wang, K. Jahn…·K. Takahashi
This study uses single-cell DNA sequencing to analyze clonal diversity in AML, revealing mutation co-occurrence, mutual exclusivity, and evolutionary patterns linked to treatment resistance and poor prognosis.
DOI 10.1038/s41467-020-19119-8