Cellular visualization of G-quadruplex RNA via fluorescence lifetime imaging microscopy
J. Robinson, S. G. Stenspil, K. Maleckaite, M. Bartlett, M. Di Antonio, R. Vilar, M. Kuimova
This paper introduces a new fluorescent probe, TOR-G4, for visualizing G-quadruplex RNA in cells using fluorescence lifetime imaging microscopy, distinguishing G4s from other structures without relying on intensity changes.
bioRxiv · May 7, 2023Biophysics