M. Di Antonio

This paper introduces a new fluorescent probe, TOR-G4, for visualizing G-quadruplex RNA in cells using fluorescence lifetime imaging microscopy, distinguishing G4s from other structures without relying on intensity changes.

This study shows that C9orf72 hexanucleotide repeat expansions form RNA condensates via multimolecular G-quadruplexes, suggesting a therapeutic target for ALS/FTD.

This study shows that Cockayne Syndrome B protein binds and resolves intermolecular G-quadruplex structures in ribosomal DNA, suggesting a role in maintaining cellular homeostasis.