Hydroxycarboxylic acid receptor 2 (HCAR2/GPR109A) expression and signaling promotes the maintenance of an immunoinhibitory retinal environment
F. Powell, A. Tawfik, P. Arjunan, D. G. Chopra, M. Al-Shabrawey, N. Singh, R. N. Jadeja, M. Kaufman, M. Jones, O. Fromal, A. Saul, W. J. Jahng, M. Bartoli, P. M. Martin
This study shows that HCAR2/GPR109A maintains an immunoinhibitory retinal environment by regulating immune cell responses and preventing inflammation in retinal diseases.
bioRxiv · Mar 15, 2021 · PreprintBiochemistry