J. Petersen

A neutral process of genome reduction in marine bacterioplankton

The paper investigates genome reduction in marine bacterioplankton, finding that neutral processes like genetic drift, not streamlining selection, drive genome size reduction in the Roseobacter group.

Rapid recall and de novo T cell responses during SARS-CoV-2 breakthrough infection

This study examines T cell responses during SARS-CoV-2 breakthrough infections, showing rapid recall of memory T cells and a correlation between CD8+ T cell activation and viral clearance.

Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells.

This study identifies KIR3DL3 expression in T cells, showing it is upregulated by unconventional stimulation and varies by individual genetic variants.

Novel torin1-sensitive phosphorylation sites on the metabolic regulator AMPK revealed by label-free mass spectrometry

The paper identifies mTORC1-sensitive phosphorylation sites on AMPK using mass spectrometry, revealing their role in regulating nuclear AMPK activity and cell proliferation under nutrient stress.

SARS-CoV-2 mRNA vaccination elicits robust and persistent T follicular helper cell response in humans

This study shows that SARS-CoV-2 mRNA vaccination leads to strong and long-lasting T follicular helper cell responses in humans.

Environmental control of Pub1 (NEDD4 family E3 ligase) in S. pombe is regulated byTORC2 and Gsk3.

The paper shows that TORC2 and Gsk3 regulate Pub1 in S. pombe, affecting amino acid transporter abundance and canavanine sensitivity under nitrogen stress.

A novel class of sulfur-containing aminolipids widespread in marine roseobacters

The paper identifies and characterizes a novel sulfur-containing aminolipid in marine roseobacters, showing its role in biofilm formation and widespread distribution in Tara Oceans metagenomes.

The hidden pangenome: comparative genomics reveals pervasive diversity in symbiotic and free-living sulfur-oxidizing bacteria

The paper performs comparative genomic analysis of Thioglobaceae bacteria to reveal pervasive intra-specific diversity and a hidden pangenome contributing to their evolutionary success.

Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS- S and MERS-S pseudotyped particles

This paper identifies six broad-spectrum inhibitors of SARS-CoV-2 and MERS-CoV spike-mediated cell entry through drug repurposing screens using pseudotyped particles.

Phylogenomic analysis reveals the basis of adaptation of Pseudorhizobium species to extreme environments

This paper reclassifies Pseudorhizobium species based on genomic analysis and identifies key functions for adaptation to extreme environments.

RootPainter: Deep Learning Segmentation of Biological Images with Corrective Annotation

RootPainter is a software tool for training deep neural networks in biological image analysis, tested on plant root datasets for segmentation tasks.

Horizontal acquisition followed by expansion and diversification of toxin-related genes in deep-sea bivalve symbionts

The paper compares toxin-related genes in symbionts of deep-sea mussels and sponges to understand their evolutionary origins and functional roles.

Chemosymbiotic bivalves contribute to the nitrogen budget of seagrass ecosystems

The paper investigates the role of lucinid bivalves and their symbionts in nitrogen cycling in seagrass ecosystems, finding they contribute significant ammonium to the ecosystem.

Diversity matters: Deep-sea mussels harbor multiple symbiont strains

The paper shows that deep-sea mussels host multiple symbiont strains with diverse metabolic functions, challenging the idea that symbiont diversity is limited in intracellular bacteria.