Author

M. Bhatt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. chakraborty· 4 shared S. Haldar· 4 shared d. Chowdhury· 3 shared D. Chaudhuri· 2 shared A. S. Alberto-Silva· 1 shared D. Maity· 1 shared E. Bossi· 1 shared H. A. Bock· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersBiophysics

S. chakraborty

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Unravelling Antibody-Induced Mechanical Stability of Antigen: Insights from Single-Molecule Studies

S. Haldar, S. Chakrabarty, S. chakraborty, S. Pandit, M. Bhatt, d. Chowdhury

This study investigates how IgM antibodies affect the mechanical stability of protein L using single-molecule techniques, revealing concentration-dependent stability increases and altered unfolding pathways.

bioRxiv · May 24, 2024 · PreprintBiophysics

Bioisosteric analogs of MDMA with improved pharmacological profile

A. S. Alberto-Silva, S. Hemmer, H. A. Bock, L. Alves da Silva, K. R. Scott, N. Kastner, M. Bhatt, M. Niello, K. Jantsch, O. Kudlacek, E. Bossi, T. Stockner, M. R. Meyer, J. D. McCorvy, S. D. Brandt, , H. H. Sitte

This study evaluates three MDMA bioisosteres for improved pharmacological profiles, finding reduced off-target receptor activity and altered hepatic metabolism compared to MDMA.

bioRxiv · Apr 8, 2024 · PreprintPharmacology & Toxicology

Methotrexate-modulated talin-dynamics drives cellular mechanical phenotypes via YAP signalling

D. Chowdhury, S. Dhabal, M. Bhatt, D. Maity, S. Chakraborty, S. Priyadarshi, S. Haldar

This study shows methotrexate modulates talin dynamics, affecting YAP signaling and cancer cell mechanical properties through focal adhesion changes.

bioRxiv · Apr 7, 2023 · PreprintCell Biology

Talin-drug interaction reveals a key molecular determinant for biphasic mechanical effect: studied under single-molecule resolution

S. Chakraborty, M. Bhatt, D. Chowdhury, D. Chaudhuri, S. Haldar

This study investigates talin-drug interactions using single-molecule techniques, revealing biphasic mechanical effects and mechanistic insights into drug-induced stability changes.

bioRxiv · Apr 4, 2022 · PreprintBiophysics

Real time observation of chaperone-modulated talin mechanics under single molecule resolution

S. Chakraborty, D. Chaudhuri, S. Banerjee, M. Bhatt, S. Haldar

This study investigates how chaperones modulate talin mechanics under single-molecule resolution, showing they alter unfolding forces and energy landscapes.

bioRxiv · Apr 27, 2021 · PreprintBiophysics