Author

D. Maity

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 2 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

D. Chowdhury· 2 shared M. I. Choudhury· 2 shared S. Haldar· 2 shared S. Priyadarshi· 2 shared A. Agrawal· 1 shared A. D. Hamilton· 1 shared A. Giri· 1 shared A. J. Afzal· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCancer Biology

D. Chowdhury

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Next-Gen Profiling of Tumor-resident Stem Cells using Machine learning

D. Chowdhury, B. Neekhra, S. Priyadarshi, S. Mukherjee, D. Maity, D. Gupta, S. Haldar

This paper introduces OSCORP, a machine learning method that identifies cancer stem cells with 99% accuracy using bulk RNAseq data, revealing CSC states and their clinical and transcriptomic signatures across 22 cancer types.

bioRxiv · Nov 24, 2023 · PreprintCancer Biology

Methotrexate-modulated talin-dynamics drives cellular mechanical phenotypes via YAP signalling

D. Chowdhury, S. Dhabal, M. Bhatt, D. Maity, S. Chakraborty, S. Priyadarshi, S. Haldar

This study shows methotrexate modulates talin dynamics, affecting YAP signaling and cancer cell mechanical properties through focal adhesion changes.

bioRxiv · Apr 7, 2023 · PreprintCell Biology

Profiling Dynamic Patterns of Single-cell Motility

D. Maity, N. Sivakumar, P. Kamat, N. Zamponi, C. Min, W. Du, H. Jayatilaka, A. Giri, A. Johnston, B. Starich, M. Karl, A. Agrawal, D. Riley, L. Venturitti, A. Melnick, , J. M. Phillip

This study introduces CaMI, a framework to classify single-cell motility patterns, revealing heterogeneity and dynamics not captured by traditional ensemble methods.

bioRxiv · Sep 21, 2022Bioengineering

Mechanical Compression Creates a Quiescent Muscle Stem Cell Niche

J. Tao, M. I. Choudhury, D. Maity, T. Kim, S. Sun, C.-M. Fan

This study shows that mechanical compression of muscle stem cells induces quiescence by altering tension and activating Notch signaling independently of canonical cleavage.

bioRxiv · Oct 2, 2021 · PreprintBiophysics

Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function

L. Palanikumar, L. Karpauskaite, S. Hassan, M. Alam, M. Al-Sayegh, I. Chehade, D. Maity, L. Ali, Z. Falls, R. Samudrala, M. Kalmouni, Y. Hunashal, J. Ahmed, S. Karapetyan, R. Pasricha, , M. Magzoub

This study identifies a small-molecule amyloid inhibitor that disrupts mutant p53 aggregation, restores its function, and reduces tumor growth in xenograft models.

bioRxiv · Aug 10, 2020Cancer Biology

Trans-epithelial Fluid Pumping Performance of Renal Epithelial Cells and Mechanics of Cystic Expansion

M. I. Choudhury, Y. Li, P. Mistriotis, E. E. Dixon, J. Yang, D. Maity, R. Walker, M. Benson, L. Martin, F. Koroma, F. Qian, K. Konstantopoulos, O. M. Woodward, S. X. Sun

This study uses a microfluidic platform to show renal epithelial cells generate hydraulic pressure gradients, with PKD cells showing reversed fluid flow and higher stall pressure.

bioRxiv · Aug 6, 2019Biophysics