CRISPR-Cas13d screens identify KILR a breast cancer risk-associated lncRNA that regulates DNA replication and repair.
L. Wang, M. Bitar, X. Lu, S. Jacquelin, S. Nair, H. Sivakumaran, K. M. Hillman, S. Kaufmann, R. Ziegman, F. Casciello, H. Gowda, J. Rosenbluh, S. L. Edwards, J. D. French
The paper identifies KILR, a breast cancer risk-associated lncRNA, and shows it regulates DNA replication and repair by sequestering RPA1.
bioRxiv · Nov 16, 2023 · PreprintCancer Biology