Author

M. Boufraqech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:CRISPR screen· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

H. Li· 2 shared U. Weyemi· 2 shared Y. Liu· 2 shared C. N. Wilson· 1 shared E. Y. Maier· 1 shared H. J. Bai· 1 shared J. E. DeVore· 1 shared M. E. Diefenbacher· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

H. Li

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Metabolism-focused CRISPR screen unveils Mitochondrial Pyruvate Carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer

T. Furusawa, R. Cavero, Y. Liu, H. Li, X. Xu, T. Andresson, W. Reinhold, O. White, M. Boufraqech, T. J. Meyer, O. Hartmann, M. E. Diefenbacher, Y. Pommier, U. Weyemi

The paper identifies MPC1 as a key driver of PARP inhibitor resistance in NSCLC lung cancer through a metabolism-focused CRISPR screen.

bioRxiv · Nov 29, 2023Cancer Biology

CRISPR metabolic screen identifies ATM and KEAP1 as targetable genetic vulnerabilities in solid tumors.

H. Li, Y. Liu, C. N. Wilson, H. J. Bai, M. Jones, S. Wang, Y. Xiao, J. E. DeVore, E. Y. Maier, M. Boufraqech, U. Weyemi

The paper identifies ATM and KEAP1 as targetable vulnerabilities in solid tumors through a CRISPR metabolic screen revealing their synthetic lethality.

bioRxiv · May 3, 2022Cancer Biology