Author

T. J. Meyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:human· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

T. Andresson· 2 shared A. Chikhalya· 1 shared A. Nussenzweig· 1 shared A. Tighe· 1 shared B. Liu· 1 shared B. Oliver· 1 shared B. Sheridan· 1 shared B. St. Croix· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersBioengineering

T. Andresson

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Engineering Tumor Stroma Morphogenesis Using Dynamic Cell-Matrix Spheroid Assembly

M. J. Buckenmeyer, E. A. Brooks, M. S. Taylor, L. Yang, R. J. Holewinski, T. J. Meyer, M. Galloux, M. Garmendia-Cedillos, T. J. Pohida, T. Andresson, B. St. Croix, M. T. Wolf

This paper develops a 3D self-assembly system to engineer tumor stroma-like structures using decellularized ECM and cancer cells, showing effects on malignancy and metabolism.

bioRxiv · Mar 19, 2024Bioengineering

Metabolism-focused CRISPR screen unveils Mitochondrial Pyruvate Carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer

T. Furusawa, R. Cavero, Y. Liu, H. Li, X. Xu, T. Andresson, W. Reinhold, O. White, M. Boufraqech, T. J. Meyer, O. Hartmann, M. E. Diefenbacher, Y. Pommier, U. Weyemi

The paper identifies MPC1 as a key driver of PARP inhibitor resistance in NSCLC lung cancer through a metabolism-focused CRISPR screen.

bioRxiv · Nov 29, 2023Cancer Biology

Differential regulation by CD47 and thrombospondin-1 of extramedullary erythropoiesis in mouse spleen

R. Banerjee, T. J. Meyer, M. C. Cam, S. Kaur, D. D. Roberts

This study shows that CD47 and thrombospondin-1 regulate extramedullary erythropoiesis in mouse spleen, with CD47 limiting it and thrombospondin-1 supporting a basal level.

bioRxiv · Sep 28, 2023Cell Biology

B cell-intrinsic STAT3-mediated support of latency and interferon suppression during murine gammaherpesvirus 68 infection revealed through an in vivo competition model

C. H. Hogan, S. M. Owens, G. V. Reynoso, V. Kirillov, T. J. Meyer, M. A. Zelazowska, B. Liu, X. Li, A. Chikhalya, Q. Dong, C. Khairallah, N. C. Reich, B. Sheridan, K. M. McBride, P. Hearing, , L. T. Krug

This study shows that B cell-intrinsic STAT3 supports gammaherpesvirus latency and suppresses interferon responses in mice, using a competitive infection model.

bioRxiv · Mar 22, 2023 · PreprintMicrobiology

TP53 loss initiates chromosomal instability in high-grade serous ovarian cancer

D. Bronder, D. Wangsa, D. Zong, T. J. Meyer, R. Wardenaar, P. Minshall, A. Tighe, D. Hirsch, K. Heselmeyer-Haddad, L. Nelson, D. Spierings, J. C. McGrail, M. Cam, A. Nussenzweig, F. Foijer, , S. S. Taylor

This study shows that TP53 loss in fallopian tube epithelial cells drives chromosomal instability through cell cycle deregulation, without requiring additional mutations.

bioRxiv · Mar 12, 2021Cancer Biology

Glycolytic metabolism of pathogenic T cells enables early detection of GvHD by 13C-MRI

J. C. Assmann, D. E. Farthing, K. Saito, N. Maglakelidze, B. Oliver, K. A. Warrick, C. Sourbier, C. J. Ricketts, T. J. Meyer, S. Z. Pavletic, W. M. Linehan, M. C. Krishna, R. E. Gress, N. P. Buxbaum

This study uses 13C-MRI to detect early glycolytic activity in T cells, enabling non-invasive GvHD detection before symptoms appear.

bioRxiv · Mar 16, 2020Immunology