Oncogenic herpesvirus engages the endothelial transcription factors SOX18 and PROX1 to increase viral genome copies and virus production
S. Gramolelli, E. Elbasani, V. Nurminen, K. Tuohinto, T. Günther, R. E. Kallinen, S. P. Kaijalainen, R. Diaz, A. Grundhoff, C. Haglund, J. M. Ziegelbauer, M. Bower, M. Francois, P. M. Ojala
This study shows that SOX18 and PROX1, endothelial transcription factors, regulate KSHV lytic replication and virus production in lymphatic endothelial cells.
bioRxiv · Aug 27, 2019Microbiology