Cancer BiologybioRxivPreprint
DLL4-Notch3-WNT5B axis is a novel mediator of bi-directional pro-metastatic crosstalk between melanoma and lymphatic endothelial cells
DOI 10.1101/2023.04.21.537773
Author
P. M. Ojala
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 28 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship4 papers
Recent·Most cited
- Cancer BiologybioRxiv
Efficacy and safety of glycosphingolipid SSEA-4 targeting CAR-T cells in an ovarian carcinoma model
H. Monzo, M. Hyytiäinen, E. Elbasani…·P. M. Ojala
This study evaluates anti-SSEA-4 CAR-T cells in ovarian cancer models, showing efficacy against SSEA-4 positive cells but highlighting dose-dependent toxicity.
DOI 10.1158/1535-7163.mct-23-0008 - MicrobiologybioRxiv
KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposis sarcoma studies
K. Tuohinto, T. A. DiMaio, E. A. Kiss…·P. M. Ojala
This study identifies KSHV-infected lymphatic endothelial colony forming cells as a novel model for studying Kaposis sarcoma, showing their ability to persist in vivo and recapitulate tumor characteristics.
DOI 10.1371/journal.ppat.1010753 - MicrobiologybioRxiv
Oncogenic herpesvirus engages the endothelial transcription factors SOX18 and PROX1 to increase viral genome copies and virus production
S. Gramolelli, E. Elbasani, V. Nurminen…·P. M. Ojala
This study shows that SOX18 and PROX1, endothelial transcription factors, regulate KSHV lytic replication and virus production in lymphatic endothelial cells.
DOI 10.1158/0008-5472.can-19-3103