Author

M. C. Gage

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Arefin· 1 shared A. Castrillo· 1 shared A. Jathanna· 1 shared B. Pourcet· 1 shared C. A. Pellet-Many· 1 shared I. C. Zachary· 1 shared I. Pineda Torra· 1 shared J. Fernando-Sayers· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperImmunology

A. Arefin

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 27, 2023

Macrophage-expressed Neuropilin 2 promotes plaque formation in ApoE knockout mice and is essential for pro-inflammatory macrophage polarisation and gene expression.

J. Fernando-Sayers, J. L. Harman, M. C. Gage…·C. A. Pellet-Many

This study shows that macrophage-expressed Neuropilin 2 promotes atherosclerosis by enhancing pro-inflammatory polarization and plaque formation in ApoE knockout mice.

DOI 10.1101/2023.09.27.558806

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivJun 20, 2022

Metformin, empagliflozin and their combination modulate ex-vivo macrophage inflammatory gene expression

A. Arefin, M. C. Gage

This study examines how metformin and empagliflozin affect macrophage inflammatory gene expression alone and in combination.

DOI 10.3390/ijms24054785

mousebulk RNA-seq

𝕏 PostBluesky

PhysiologybioRxivDec 4, 2017

Disrupting myeloid-specific LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation

M. C. Gage, N. Becares-Salles, R. Louie…·I. Pineda Torra

This study shows that disrupting myeloid-specific LXRα phosphorylation increases FoxM1 expression and alters atherosclerosis by promoting macrophage proliferation and changing plaque composition.

DOI 10.1073/pnas.1721245115

mousebulk RNA-seq

𝕏 PostBluesky