Author

M. C. McCabe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 4 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

K. C. Hansen· 3 shared A. J. Saviola· 2 shared L. R. Schmitt· 2 shared A. Barrett· 1 shared A. Burlingame· 1 shared A. Neumann· 1 shared B. Lomonte· 1 shared B. W. Perry· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersBiochemistry

K. C. Hansen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Assessing Heterogeneity in the N-Telopeptides of Type I Collagen by Mass Spectrometry

Z. Darula, M. C. McCabe, A. Barrett, L. R. Schmitt, M. D. Maslanka, A. J. Saviola, J. Orgel, A. Burlingame, C. A. Staab-Weijnitz, K. Stenmark, V. Weaver, R. J. Chalkley, K. C. Hansen

The paper develops a method to identify N-terminal cross-linked peptides from collagen I in Achilles tendon using mass spectrometry, revealing differences in cross-links in bovine pulmonary hypertension.

bioRxiv · Mar 31, 2024 · PreprintBiochemistry

PDGFRα/β heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation

M. B. Campana, M. R. Perkins, M. C. McCabe, A. Neumann, E. D. Larson, K. A. Fantauzzo

PDGFR/{beta} heterodimer binding to MYO1D promotes rapid internalization, inhibiting ERK1/2 phosphorylation and reducing cell proliferation.

bioRxiv · Dec 27, 2023Cell Biology

ASSESSING TARGET SPECIFICITY OF THE SMALL MOLECULE INHIBITOR MARIMASTAT TO SNAKE VENOM TOXINS: A NOVEL APPLICATION OF THERMAL PROTEOME PROFILING

C. F. Smith, C. M. Modahl, D. Ceja-Galindo, K. Y. Larson, S. P. Maroney, L. Bahrabadi, N. P. Brandehoff, B. W. Perry, M. C. McCabe, D. Petras, B. Lomonte, J. J. Calvete, T. A. Castoe, S. P. Mackessy, K. C. Hansen, A. J. Saviola

This study uses Thermal Proteome Profiling and PISA to assess marimastat's specificity against snake venom toxins, identifying its targets and interactions with specific proteoforms.

bioRxiv · Oct 25, 2023Biochemistry

Evaluation and refinement of sample preparation methods for extracellular matrix proteome coverage

M. C. McCabe, L. R. Schmitt, R. C. Hill, M. Dzieciatkowska, M. Maslanka, W. F. Daamen, T. H. van Kuppevelt, D. J. Hof, K. C. Hansen

The paper evaluates and refines sample preparation methods to improve ECM proteome coverage, achieving a 4-fold increase in unique ECM peptide identifications.

bioRxiv · Nov 25, 2020Biochemistry