Inflammation Drives Alternative First Exon usage to Regulate Immune Genes including a Novel Iron Regulated Isoform of Aim2
E. K. Robinson, P. Jagannatha, S. Covarrubias, M. Cattle, R. Safavi, R. Song, K. Viswanathan, R. Abu-Shumays, M. Jain, S. M. Cloonan, E. K. Wakeland, M. Akeson, A. N. Brooks, S. Carpenter
The paper identifies inflammation-induced alternative first exon usage in immune genes, revealing a novel iron-regulated Aim2 isoform with a 5′UTR iron-responsive element.
bioRxiv · Jul 6, 2020Immunology